Difference in sequence is the cause of difference in transformations.

Krama is sequence, order. Anyatva is difference. Pariṇāma is transformation. Hetu is cause.

Why do things transform in different ways? Because of difference in the sequence of causes.

The same clay can become a pot or a brick depending on the sequence of actions applied. Order matters.

This sutra explains the diversity of the manifest world. The same primordial causes (the guṇas) produce different results depending on how they combine and in what order.

It also has practical implications for the yogī: changing the sequence changes the result. By modifying the order of practices, the effects are modified.

Vyāsa relates this to time. Time is not a separate entity but the succession of moments itself. The temporal sequence determines what manifests.

Understanding krama is understanding how change operates. And understanding change is the prelude to transcending it.